643 Grand, South San Francisco CA 94080 for sale - Presented to you by Terrence Griffin of San Diego California
Listing provided courtesy of Jill Penna of Christie's International Real Estate Sereno. Last updated 2026-08-29 08:17:18.000000. Listing information © 2026 Sandicor.

Asking Price: $1,248,000 | ​​​​​​​

643 Grand, South San Francisco CA 94080

Community: ​699 - Not Defined


This Single Family Residence property was built in 1895 and is priced at $1,248,000. Please see the additional details below.
  • 1,630 Sq Ft
  • 4 bathrooms
  • 3 bedrooms
  • MLS#: ML82059314
  • Type: Single Family Residence
  • Year Built: 1895
Ideally located near Downtown South San Francisco and the cities thriving biotech and life-sciences corridor, 643 Grand Avenue where space, comfort, and a remarkable garden setting come together in the heart of South San Francisco. 643 Grand Avenue offers a spacious and versatile layout with excellent access to major transportation and employment centers. The home features 3 bedrooms and 4 bathrooms, with a private full bathroom for each bedroom. Additional highlights include high ceilings, abundant natural light, hardwood floors, a full basement with ample storage, and a detached 2-car garage equipped with a 220-volt outlet for EV charging. The home also features a water purification system, tankless water heater, and water softener. The quaint lot includes a freshly manicured organic vegetable garden with sunflowers and offers potential for an ADU. Conveniently located near Downtown South San Francisco, Genentech, Caltrain, US-101, and I-280.

Call or Email Terrence Griffin now to inquire about this property

619-952-0152